Marplan® (isocarboxazid) Tablets Patient Assistance Program
If you cannot afford your Marplan® (isocarboxazid) Tablets prescription, Validus Pharmaceuticals LLC. may be able to help. The Marplan® (isocarboxazid) Tablets Patient Assistance Program provides Marplan® (isocarboxazid) Tablets at no charge to eligible patients. To qualify, a patient must be a resident of the United States and meet certain financial requirements. Once approved, patients will receive a 3-month supply of Marplan® (isocarboxazid) Tablets (delivered to their healthcare provider’s office).
For full details, or to request a program application, call 1-866-9VALIDUS (1-866-982-5438) from 9AM to 5PM (except holidays).
Please Note: One section of your application must be completed by the healthcare provider prescribing Marplan® (isocarboxazid) Tablets. Validus Pharmaceuticals LLC. reserves the right to modify the Patient Assistance Program with respect to any patient, or in its entirety, at any time. Third-party payment is affected by many factors and, therefore, Validus Pharmaceuticals LLC. cannot guarantee that you will be successful in obtaining insurance payments.
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Please see Full Prescribing Information including BOXED WARNINGS regarding increased risk of suicidality in children and adolescents. MAO Inhibitors are contraindicated with certain drugs. Potential hypertensive crises may occur with foods that contain tyramine. As with all antidepressants, patients should be observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of treatment.
Suicidality and Antidepressant Drugs
Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies with Major Depressive Disorder (MDD) and other psychiatric disorders. Anyone considering the use of Marplan® (isocarboxazid) Tablets or any other antidepressant in a child, adolescent or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Marplan® (isocarboxazid) Tablets is not approved for use in pediatric patients. (See Warnings: Clinical Worsening and Suicide Risk, Precautions: Information for Patients, and Precautions: Pediatric Use).
Pooled analyses of short-term (4 to 16 weeks) placebo-controlled trials of 9 antidepressant drugs (SSRIs and others) in children and adolescents with major depressive disorder (MDD), obsessive compulsive disorder (OCD), or other psychiatric disorders (a total of 24 trials involving over 4400 patients) have revealed a greater risk of adverse events representing suicidal thinking or behavior (suicidality) during the first few months of treatment in those receiving antidepressants. The average risk of such events in patients receiving antidepressants was 4%, twice the placebo risk of 2%. No suicides occurred in these trials.