Overall, MARPLAN has been well tolerated by many patients. The table below shows the side effects seen in more than 5% of patients taking MARPLAN.
Adverse events seen in ≥5% of patients in clinical trials with MARPLAN doses of 40 to 80 mg/day
|Placebo||MARPLAN <50mg||MARPLAN ≥50mg|
The most common reasons patients discontinued taking MARPLAN were dizziness, feeling faint/light-headed, low blood pressure, and dry mouth.
If you experience side effects with MARPLAN, talk to your doctor.
Because of its potentially serious side effects, MARPLAN should not be considered as the first choice for the treatment of depression, but should be considered when other antidepressants have failed to control symptoms of depression. You should talk to your healthcare provider about the benefits and risks associated with treatment.
MARPLAN is not for use in children and adolescents. Antidepressant medicines such as MARPLAN may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have (or have a family history of) bipolar illness (also called manic-depressive illness) or suicidal thoughts or actions. You should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings when taking MARPLAN, especially when starting treatment or when the dose is changed. Call your healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
What is the most important information I should know about MARPLAN?
Foods you CANNOT eat:
In general, you should avoid foods that are aged to increase flavor.
|Meat, Poultry and Fish|
|Dairy (milk products)|
|Fruits and Vegetables|
Who should not take MARPLAN?
Do not take MARPLAN if you
What should I tell my healthcare provider before taking MARPLAN?
Some medications can interact with MARPLAN and cause serious unwanted effects. To avoid these effects, be sure to tell your doctor about ALL of the other medications you are taking, including herbal supplements.
Before you take MARPLAN, tell your healthcare provider if you have any of the following conditions:
The most common side effects of MARPLAN include
These are not all the possible side effects of MARPLAN. For more information, ask your healthcare provider or pharmacist. Tell your healthcare provider if you have any side effects that bothers you or that does not go away.
Please refer to the full Prescribing Information for a list of inactive ingredients found at www.marplan.com.
What should I avoid while taking MARPLAN?
See the Contraindications section of the full Prescribing Information for a complete list of drugs to avoid.
The risk information provided here is not comprehensive. To learn more, talk about MARPLAN with your doctor or pharmacist. The FDA-approved product labeling can be found at www.marplan.com or 1-866-982-5438.
You may report side effects to the FDA at 1-800-FDA-1088, or at www.fda.gov/medwatch. You may also report side effects to VALIDUS at 1-866-982-5438 or [email protected].
MARPLAN is available by prescription only.
Please see the accompanying Medication Guide at www.marplan.com.